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Breaking AI developments, in-depth guides, real-world case studies, and analysis — each one rated so you know what matters.
Roche pays $2.3B for blood cancer drug that degrades BTK protein
Roche and Nurix licensed bexobrutideg, an oral BTK degrader, in a deal worth up to $2.3 billion. The drug targets B-cell malignancies and enters Phase III trials this summer.
Incyte pays $2bn for VGA039, a monthly shot for bleeding disorders
Incyte will spend up to $2 billion to acquire Vega Therapeutics and its late-stage von Willebrand disease candidate. The drug could displace frequent IV infusions with once-monthly dosing.
90% of blockbuster drugs lack biosimilar competitors—why pricing kills the pipeline
A 2025 IQVIA analysis found 90% of biologics losing patent protection this decade have no biosimilar in development. Samsung Bioepis exec explains why: broken economics, not broken science.
Pfizer's Hympavzi Now Covers Kids 6+ With Haemophilia A or B
FDA expanded Hympavzi approval to children aged 6–11 and adolescents 12+ with inhibitors. The once-weekly injection showed 93% bleeding reduction versus on-demand IV treatment in Phase III trials.
J&J buys Firefly Bio for $1B to target KRAS cancers
Johnson & Johnson is acquiring Firefly Bio for $1 billion to add its Firelink degrader-antibody conjugate platform to its oncology pipeline. The deal targets KRAS-driven solid tumors, where treatment options remain limited.
Spain's pharma sector pulls €1.5B in annual R&D as multinationals expand
Spain ranks third in EU scientific output and leads Europe in clinical trials approved annually. Merck, Eli Lilly, Bayer, and a dozen other pharma giants are investing billions. Here's why the country is becoming a magnet for life science capital.
CRISPR Targets p53 Mutations in Half of All Cancers
Jennifer Doudna's lab engineered a CRISPR system that kills cancer cells by recognizing mutant p53 mRNA with single-nucleotide precision. Mouse studies show the approach works on lung and liver tumors.
Lawyers Can Now Catch AI-Invented Case Citations Before Filing
BrentWorks launched CiteSentinel to scan legal briefs for fabricated cases, statutes, and authorities before they reach a judge. The tool works on your own drafts, co-counsel submissions, and opposing filings.
Institut Pasteur Funds $17M Chikungunya Vaccine Trial Across Africa
EU-backed ACT-CHIK project will test MV-CHIK vaccine in Rwanda, Kenya, Nigeria, and Senegal while preparing local manufacturing. Here's what the trial covers and why African vaccine sovereignty matters.
AI designs caffeine-triggered kill switch for CAR T cells
Texas A&M researchers used protein design to turn caffeine into a molecular off-switch for engineered cells. The system could let doctors pause cell therapies without destroying them.
95% of Detectable HIV in Treated Patients Is Defective RNA
Johns Hopkins researchers found that nearly all persistent viral traces in people on long-term HIV therapy are non-infectious copies. A new diagnostic tool could spare patients unnecessary drug changes and anxiety.
Antibiotic resistance genes found across all world oceans
Italian-led SeA Care project detected resistance genes in over 140 ocean sites across five basins, with highest concentrations near shipping routes and coastal cities. Study suggests oceans function as a global reservoir for land-based pollution.